Table 1. High-risk Populations Recommended for Pre-exposure HAV Vaccination by the Advisory Committee on Immunization Practices, U.S.P.H.S.  (Reference 10) 

• Children in communities with HAV attack rates twice the national average or those experiencing periodic outbreaks

• Children in communities with HAV attack rates above the national average (at discretion of local public health officials)

• Travelers to endemic regions

•  Individuals from non-endemic regions working in HAV endemic countries

•  Individuals with chronic liver disease or recipients of liver transplants

• Recipients of solvent/detergent treated clotting factor concentrates

• Homosexual and bisexual men

• Injecting and non-injecting illicit drug users

• Individuals who work with HAV or HAV-infected nonhuman primates

• Food handlers, depending on local conditions (at discretion of local public health officials)

Table 2. Other Potentially High-Risk Populations for Pre-Exposure HAV Vaccination (But Not Currently Recommended by the Advisory Committee on Immunization Practices) 

• Sewage and waste-water treatment plant workers

• Employees of day-care centers, institutions for developmentally disadvantaged

• Health care workers in neonatal intensive care units

Table 3. Characteristics of the Inactivated HAV Vaccines Commercially Available In the United States 

 +EL.U = ELISA units   *1 unit = 1 ng HAV antigen