Successful treatment of widely disseminated acanthamoebiasis

South Med J. 1999 Jan;92(1):55-7. doi: 10.1097/00007611-199901000-00010.

Abstract

Disseminated Acanthamoeba infections are almost invariably fatal, with no universally accepted standard for treatment. Reports of acanthamoebiasis in non-human-immunodeficiency-virus infected hosts are rare. We successfully treated a lung transplant patient who had disseminated acanthamoebiasis using a combination of pentamidine, 5-fluorocytosine, itraconazole, and topical chlorhexidine gluconate/ketoconazole cream.

Publication types

  • Case Reports

MeSH terms

  • Acanthamoeba*
  • Adult
  • Amebiasis / drug therapy*
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Antiprotozoal Agents / therapeutic use
  • Azithromycin / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Lung Transplantation
  • Pentamidine / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Antiprotozoal Agents
  • Itraconazole
  • Pentamidine
  • Azithromycin