Cytomegalovirus-induced alveolar hemorrhage in patients with AIDS: a new clinical entity?

Clin Infect Dis. 1996 Apr;22(4):616-20. doi: 10.1093/clinids/22.4.616.

Abstract

We report five cases of alveolar hemorrhage associated with intravascular hemolysis in patients with AIDS. Cytomegalovirus was the only pathogen recovered from the lungs of these patients. There was evidence of multivisceral spread of the virus in all patients, and all had viremia. All had clinical, biological, and pathological features of pulmonary vasculitis, and the conditions of four improved with specific anti-cytomegalovirus therapy.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / virology*
  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / diagnosis
  • Cytomegalovirus Infections / drug therapy
  • Female
  • Hemolysis
  • Hemorrhage / diagnosis
  • Hemorrhage / drug therapy
  • Hemorrhage / virology*
  • Humans
  • Lung Diseases / complications*
  • Lung Diseases / diagnosis
  • Lung Diseases / drug therapy
  • Lung Diseases / virology
  • Male
  • Middle Aged
  • Pulmonary Alveoli*
  • Vasculitis / drug therapy
  • Vasculitis / virology