Treatment of central venous catheter occlusions with ethanol and hydrochloric acid

JPEN J Parenter Enteral Nutr. 1995 Sep-Oct;19(5):416-8. doi: 10.1177/0148607195019005416.

Abstract

Background: Occluded central venous lines (CVLs) is a major problem in pediatric patients.

Methods: To relieve obstructed catheters, infusions of ethanol (up to 3 mL of a 70% solution) for presumed lipid occlusions and hydrochloric acid (HCl, 0.1 N, up to 3 mL) for presumed mineral and drug precipitates were given in an attempt to relieve obstructed catheters.

Results: Patency was restored in 34 of 39 occluded catheters over an 18-month period.

Conclusions: Clearing occluded CVLs with ethanol and HCl is not only beneficial to the patient but also offers considerable cost savings compared to CVL replacement.

MeSH terms

  • Catheterization, Central Venous / instrumentation*
  • Child
  • Equipment Failure
  • Ethanol / administration & dosage*
  • Humans
  • Hydrochloric Acid / administration & dosage*
  • Parenteral Nutrition, Total / economics
  • Parenteral Nutrition, Total / instrumentation*
  • Urokinase-Type Plasminogen Activator / administration & dosage

Substances

  • Ethanol
  • Urokinase-Type Plasminogen Activator
  • Hydrochloric Acid