Creeping eruption. A review of clinical presentation and management of 60 cases presenting to a tropical disease unit

Arch Dermatol. 1993 May;129(5):588-91. doi: 10.1001/archderm.129.5.588.

Abstract

Background and design: Cutaneous larva migrans is an infection with a larval nematode, most frequently by dog or cat hookworms. It has a characteristic presentation that is easily recognizable. We reviewed the charts of 60 patients with cutaneous larva migrans who presented to the Tropical Disease Unit, Toronto (Ontario) Hospital, during a 6-year period.

Results: Ninety-five percent of the patients were Canadians who had recently returned from the tropics or subtropics, notably the Caribbean. Almost all patients had a linear or serpiginous, very pruritic larval track. Topical thiabendazole was efficacious in 52 (98%) of 53 patients treated. Albendazole cured six (88%) of seven patients treated. Because of adverse effects, oral thiabendazole and liquid nitrogen were not utilized.

Conclusion: We conclude that topical thiabendazole and oral albendazole are very effective and safe modalities for the treatment of cutaneous larva migrans.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Albendazole / therapeutic use*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Larva Migrans / drug therapy*
  • Larva Migrans / epidemiology
  • Male
  • Middle Aged
  • Thiabendazole / therapeutic use*

Substances

  • Albendazole
  • Thiabendazole