Rhinoscleroma: a growing concern in the United States? Mayo Clinic experience

Mayo Clin Proc. 1993 Dec;68(12):1151-7. doi: 10.1016/s0025-6196(12)60064-0.

Abstract

Rhinoscleroma is a chronic, progressive, granulomatous infection of the upper airways caused by the bacterium Klebsiella rhinoscleromatis. Although most cases occur in developing countries, recent immigration patterns have led to an increasing number of patients with rhinoscleroma in the United States. Rhinoscleroma may mimic various inflammatory and neoplastic processes, including leprosy, paracoccidioidomycosis, sarcoidosis, basal cell carcinoma, and Wegener's granulomatosis. Current therapy consists of a combination of surgical débridement and prolonged antimicrobial therapy. Rhinoscleroma should be added to the list of opportunistic infections that can occur in patients with human immunodeficiency virus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Combined Modality Therapy
  • Debridement
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Retrospective Studies
  • Rhinoscleroma / diagnosis
  • Rhinoscleroma / epidemiology*
  • Rhinoscleroma / therapy
  • United States / epidemiology

Substances

  • Anti-Bacterial Agents