Abstract
We describe the clinical course and successful treatment of a previously healthy man who, after experiencing trauma, presented with severe cutaneous mucormycosis due to Apophysomyces elegans and subsequently developed secondary renal infection. A multidisciplinary approach employing aggressive surgical debridement and therapy with hyperbaric oxygen, liposomal amphotericin B, and interferon-gamma was successful in controlling his infection, obviating the need for nephrectomy.
MeSH terms
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Adult
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Amphotericin B / therapeutic use
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Humans
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Hyperbaric Oxygenation
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Interferon-gamma / therapeutic use
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Kidney Diseases / diagnostic imaging
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Kidney Diseases / microbiology
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Kidney Diseases / therapy*
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Liposomes
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Male
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Mucorales / growth & development
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Mucorales / isolation & purification
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Mucormycosis / therapy*
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Soft Tissue Infections / microbiology
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Soft Tissue Infections / therapy*
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Soft Tissue Injuries / microbiology*
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Tomography, X-Ray Computed
Substances
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Liposomes
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Amphotericin B
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Interferon-gamma