Abstract
Seventeen cases of infections due to Cunninghamella species have been reported worldwide in humans, and there have been only three survivors. We report a case of paranasal sinusitis due to Cunninghamella bertholletiae in an elderly patient who had diabetes mellitus and myelodysplasia. After receiving 7 weeks of therapy with deoxycholate amphotericin B (44 mg/kg or a total of 3 g) and rifampin, the patient was cured and did not have to undergo radical surgery.
MeSH terms
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Aged
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Amphotericin B / therapeutic use*
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Diabetes Mellitus, Type 2 / complications
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Drug Therapy, Combination
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Ethmoid Sinusitis / diagnostic imaging
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Ethmoid Sinusitis / drug therapy*
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Ethmoid Sinusitis / microbiology
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Humans
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Male
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Maxillary Sinusitis / diagnostic imaging
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Maxillary Sinusitis / drug therapy*
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Maxillary Sinusitis / microbiology
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Mucorales / isolation & purification
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Mucormycosis / complications
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Mucormycosis / drug therapy*
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Myelodysplastic Syndromes / complications
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Paranasal Sinuses / microbiology
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Rifampin / therapeutic use*
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Tomography, X-Ray Computed