Intravenous streptomycin: a useful route of administration

Clin Infect Dis. 1994 Dec;19(6):1150-1. doi: 10.1093/clinids/19.6.1150.

Abstract

Streptomycin is an aminoglycoside antibiotic that is indicated for the treatment of tuberculous and nontuberculous infections. Intramuscular injection is the recommended route of administration. There are few reports on intravenous administration of streptomycin. We describe the use of intravenous streptomycin to treat endocarditis due to a strain of Enterococcus faecalis with high-level resistance to gentamicin. Physicians should consider the intravenous route as an alternate method of administering streptomycin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Bacteremia / microbiology
  • Endocarditis, Bacterial / drug therapy*
  • Enterococcus faecalis / drug effects
  • Enterococcus faecalis / isolation & purification
  • Gram-Positive Bacterial Infections / drug therapy*
  • Humans
  • Infusions, Intravenous
  • Male
  • Streptomycin / administration & dosage*
  • Streptomycin / therapeutic use

Substances

  • Streptomycin