Synergism between vancomycin and gentamicin or tobramycin for methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains

Antimicrob Agents Chemother. 1982 Nov;22(5):903-5. doi: 10.1128/AAC.22.5.903.

Abstract

By the time-kill curve method, the combinations of vancomycin-gentamicin and vancomycin-tobramycin were shown to be synergistic against a majority of methicillin-susceptible and -resistant strains of Staphylococcus aureus.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Drug Synergism
  • Gentamicins / pharmacology*
  • Methicillin / pharmacology*
  • Microbial Sensitivity Tests
  • Penicillin Resistance
  • Staphylococcus aureus / drug effects*
  • Tobramycin / pharmacology*
  • Vancomycin / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Gentamicins
  • Vancomycin
  • Methicillin
  • Tobramycin