Failure of erythromycin in treatment of Legionella micdadei pneumonia

Am J Med. 1984 Feb;76(2):318-20. doi: 10.1016/0002-9343(84)90793-9.

Abstract

A 59-year-old immunocompromised woman had nosocomial Legionella micdadei infection that failed to respond to two weeks of erythromycin in high intravenous doses and oral rifampin. Treatment with intravenous trimethoprim-sulfamethoxazole and oral rifampin, which previously has not been used in this infection, resulted in cure.

Publication types

  • Case Reports

MeSH terms

  • Drug Combinations / administration & dosage
  • Drug Therapy, Combination
  • Erythromycin / pharmacology
  • Erythromycin / therapeutic use*
  • Female
  • Humans
  • Legionella / drug effects
  • Legionnaires' Disease / drug therapy*
  • Microbial Sensitivity Tests
  • Middle Aged
  • Rifampin / administration & dosage
  • Sulfamethoxazole / administration & dosage
  • Trimethoprim / administration & dosage
  • Trimethoprim, Sulfamethoxazole Drug Combination

Substances

  • Drug Combinations
  • Erythromycin
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Sulfamethoxazole
  • Rifampin