Abstract
A randomised clinical trial in 124 adult patients with typhoid fever, proved by blood culture, showed that amoxycillin in a dosage of 1 g. six-hourly for fourteen days is an alternative to chloramphenicol, which has hitherto been regarded as the drug of choice.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Adolescent
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Adult
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Aged
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Amoxicillin* / administration & dosage
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Amoxicillin* / therapeutic use
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Ampicillin / analogs & derivatives*
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Carrier State / drug therapy
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Child
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Chloramphenicol / administration & dosage
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Chloramphenicol / therapeutic use*
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Clinical Trials as Topic
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Drug Evaluation
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Female
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Recurrence
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Salmonella typhi / isolation & purification
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Time Factors
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Typhoid Fever / drug therapy*
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Typhoid Fever / microbiology
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Typhoid Fever / mortality
Substances
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Chloramphenicol
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Ampicillin
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Amoxicillin