Abstract
Herpes simplex virus establishes a persistent, latent infection in spinal ganglia after mice have recovered from posterior paralysis. Infectious virus is replicated when these ganglia are explanted and maintained as organ cultures in vitro.
MeSH terms
-
Animals
-
Culture Techniques
-
Ganglia, Spinal / microbiology*
-
Ganglia, Spinal / pathology
-
Herpesviridae Infections / immunology
-
Herpesviridae Infections / microbiology
-
Herpesviridae Infections / pathology
-
Mice
-
Microscopy, Electron
-
Neutralization Tests
-
Simplexvirus / isolation & purification*
-
Time Factors
-
Virus Replication