Treatment of Listeria monocytogenes infection with trimethoprim-sulfamethoxazole: case report and review of the literature

Rev Infect Dis. 1986 May-Jun;8(3):427-30. doi: 10.1093/clinids/8.3.427.

Abstract

A 55-year-old female recipient of an orthotopic liver transplant, who was receiving azathioprine, prednisone and cyclosporin, developed bacteremia due to Listeria monocytogenes. Because of a penicillin allergy, the patient was treated primarIly with trimethoprim-sulfamethoxazole, to which she responded well. The prior literature on use of trimethoprim-sulfamethoxazole in listeria infections is reviewed, and future recommendations are considered. On the basis of the experience described in this case report as well as a review of the literature, trimethoprim-sulfamethoxazole appears to be an effective treatment of listeria infections.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Drug Combinations / therapeutic use
  • Female
  • Humans
  • Immunosuppression Therapy
  • Listeriosis / drug therapy*
  • Liver Transplantation
  • Middle Aged
  • Sepsis / drug therapy
  • Sulfamethoxazole / therapeutic use*
  • Trimethoprim / therapeutic use*
  • Trimethoprim, Sulfamethoxazole Drug Combination

Substances

  • Drug Combinations
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Trimethoprim
  • Sulfamethoxazole