Tricuspid valve Candida endocarditis. Successful treatment with valve-sparing debridement and antifungal chemotherapy in a multiorgan transplant recipient

Am J Med. 1986 Jan;80(1):116-8. doi: 10.1016/0002-9343(86)90059-8.

Abstract

Tricuspid valve Candida albicans endocarditis developed in a multiple-organ transplant recipient six months after successful treatment of Candida peritonitis. She has had no recurrence or valvular incompetence two years after valve-sparing debridement of the vegetation and prolonged therapy with amphotericin B. This is the second report of long-term success following valve-sparing debridement for tricuspid valve Candida endocarditis. In selected patients without annular involvement or gross valve destruction, excision of the fungal vegetation may allow for long-term cure and a competent valve.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Candidiasis / therapy*
  • Combined Modality Therapy
  • Debridement
  • Endocarditis / etiology
  • Endocarditis / therapy*
  • Female
  • Humans
  • Ketoconazole / therapeutic use
  • Kidney Transplantation*
  • Pancreas Transplantation*
  • Time Factors
  • Tricuspid Valve / surgery*

Substances

  • Antifungal Agents
  • Amphotericin B
  • Ketoconazole