Abstract
Two patients with tuberculous meningitis and internuclear ophthalmoplegia are described. Despite treatment with anti-tuberculosis chemotherapy and corticosteroids, both patients died. In one case autopsy showed severe basal meningitis with diffuse brain stem infarction secondary to widespread vasculitis.
MeSH terms
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Adult
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Brain Stem / blood supply
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Cerebral Infarction / complications
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Dexamethasone / therapeutic use
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Drug Therapy, Combination
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Endarteritis / complications
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Endarteritis / drug therapy
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Humans
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Isoniazid / therapeutic use
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Male
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Middle Aged
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Ophthalmoplegia / drug therapy
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Ophthalmoplegia / etiology*
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Prognosis
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Pyrazinamide / therapeutic use
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Rifampin / therapeutic use
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Tuberculosis, Meningeal / complications*
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Tuberculosis, Meningeal / drug therapy
Substances
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Pyrazinamide
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Dexamethasone
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Isoniazid
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Rifampin