Incidence and trends of blastomycosis-associated hospitalizations in the United States

PLoS One. 2014 Aug 15;9(8):e105466. doi: 10.1371/journal.pone.0105466. eCollection 2014.

Abstract

We used the State Inpatient Databases from the United States Agency for Healthcare Research and Quality to provide state-specific age-adjusted blastomycosis-associated hospitalization incidence throughout the entire United States. Among the 46 states studied, states within the Mississippi and Ohio River valleys had the highest age-adjusted hospitalization incidence. Specifically, Wisconsin had the highest age-adjusted hospitalization incidence (2.9 hospitalizations per 100,000 person-years). Trends were studied in the five highest hospitalization incidence states. From 2000 to 2011, blastomycosis-associated hospitalizations increased significantly in Illinois and Kentucky with an average annual increase of 4.4% and 8.4%, respectively. Trends varied significantly by state. Overall, 64% of blastomycosis-associated hospitalizations were among men and the median age at hospitalization was 53 years. This analysis provides a complete epidemiologic description of blastomycosis-associated hospitalizations throughout the endemic area in the United States.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Blastomycosis / epidemiology*
  • Blastomycosis / therapy
  • Female
  • Hospitalization / trends
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • United States / epidemiology