Diagnosis of ureaplasma urealyticum septic polyarthritis by PCR assay and electrospray ionization mass spectrometry in a patient with acute lymphoblastic leukemia

J Clin Microbiol. 2014 Sep;52(9):3456-8. doi: 10.1128/JCM.00963-14. Epub 2014 Jun 23.

Abstract

We report a case of polyarthritis with axial involvement in a young female patient treated for acute lymphoblastic leukemia. Detection in the hip fluid of Ureaplasma urealyticum by broad-range PCR followed by electrospray ionization mass spectrometry allowed the diagnosis of septic arthritis and ad integrum recovery upon adapted antibiotic therapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis / diagnosis*
  • Arthritis / drug therapy
  • Arthritis / pathology
  • Arthritis, Infectious / diagnosis*
  • Arthritis, Infectious / drug therapy
  • Arthritis, Infectious / pathology
  • Female
  • Humans
  • Polymerase Chain Reaction*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Spectrometry, Mass, Electrospray Ionization*
  • Treatment Outcome
  • Ureaplasma Infections / diagnosis*
  • Ureaplasma Infections / drug therapy
  • Ureaplasma Infections / pathology
  • Ureaplasma urealyticum / chemistry
  • Ureaplasma urealyticum / genetics
  • Ureaplasma urealyticum / isolation & purification*

Substances

  • Anti-Bacterial Agents