Chiasmitis caused by Mycobacterium haemophilum in an immunocompromised adult

Clin Imaging. 2014 Sep-Oct;38(5):727-9. doi: 10.1016/j.clinimag.2014.02.012. Epub 2014 Feb 28.

Abstract

We report a case of chiasmitis caused by a rare nontuberculous mycobacterium in an immunocompromised patient. A 44-year-old man with a history of AIDS presented with recurrent vision loss and headache. Magnetic resonance imaging (MRI) demonstrated an enhancing mass involving the optic chiasm. Histopathologic and microbiological evaluation revealed infection with Mycobacterium haemophilum. While combination antimicrobial and steroid therapy contributed to improvement in his vision, the patient's symptoms recurred. Follow-up MRI showed extension of infection to the hypothalamus and leptomeninges, indicative of basilar meningitis. MRI is a valuable tool for early diagnosis of chiasmitis as well as for monitoring infection progression and treatment response.

Keywords: Chiasmitis; MRI; Mycobacterium haemophilum.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Eye Infections, Bacterial / diagnosis*
  • Eye Infections, Bacterial / immunology
  • Eye Infections, Bacterial / microbiology
  • Humans
  • Immunocompromised Host*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Mycobacterium Infections / diagnosis*
  • Mycobacterium Infections / immunology
  • Mycobacterium Infections / microbiology
  • Mycobacterium haemophilum / isolation & purification*
  • Optic Chiasm / microbiology
  • Optic Chiasm / pathology*
  • Optic Nerve Diseases / diagnosis*
  • Optic Nerve Diseases / immunology
  • Optic Nerve Diseases / microbiology
  • Recurrence