Clinical manifestations of Eosinophilic meningitis due to infection with Angiostrongylus cantonensis in children

Korean J Parasitol. 2013 Dec;51(6):735-8. doi: 10.3347/kjp.2013.51.6.735. Epub 2013 Dec 31.

Abstract

Eosinophilic meningitis, caused by the nematode Angiostrongylus cantonensis, is prevalent in northeastern Thailand, most commonly in adults. Data regarding clinical manifestations of this condition in children is limited and may be different those in adults. A chart review was done on 19 eosinophilic meningitis patients aged less than 15 years in Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, Thailand. Clinical manifestations and outcomes were reported using descriptive statistics. All patients had presented with severe headache. Most patients were males, had fever, nausea or vomiting, stiffness of the neck, and a history of snail ingestion. Six patients had papilledema or cranial nerve palsies. It was shown that the clinical manifestations of eosinophilic meningitis due to A. cantonensis in children are different from those in adult patients. Fever, nausea, vomiting, hepatomegaly, neck stiffness, and cranial nerve palsies were all more common in children than in adults.

Keywords: Angiostrongylus cantonensis; children; clinical manifestation; eosinophilic meningitis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Angiostrongylus cantonensis / isolation & purification*
  • Animals
  • Child
  • Child, Preschool
  • Eosinophilia / complications
  • Eosinophilia / etiology
  • Eosinophilia / pathology*
  • Female
  • Humans
  • Male
  • Meningitis / complications
  • Meningitis / etiology
  • Meningitis / pathology*
  • Middle Aged
  • Patient Outcome Assessment
  • Strongylida Infections / parasitology
  • Strongylida Infections / pathology*
  • Thailand
  • Young Adult