Recurrences of visceral leishmaniasis caused by Leishmania siamensis after treatment with amphotericin B in a seronegative child

Seksit Osatakul; Mathirut Mungthin; Suradej Siripattanapipong; Atitaya Hitakarun; Rommanee Kositnitikul; Tawee Naaglor; Saovanee Leelayoova

doi:10.4269/ajtmh.13-0398

Recurrences of visceral leishmaniasis caused by Leishmania siamensis after treatment with amphotericin B in a seronegative child

Am J Trop Med Hyg. 2014 Jan;90(1):40-2. doi: 10.4269/ajtmh.13-0398. Epub 2013 Nov 25.

Authors

Seksit Osatakul¹, Mathirut Mungthin, Suradej Siripattanapipong, Atitaya Hitakarun, Rommanee Kositnitikul, Tawee Naaglor, Saovanee Leelayoova

Affiliation

¹ Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand; Department of Parasitology, Phramongkutklao College of Medicine, Bangkok 10400, Thailand.

Abstract

We report the first case of visceral leishmaniasis caused by Leishmania siamensis in a seronegative child. She was treated with amphotericin B at 1 mg/kg/day for 3 weeks; however, recurrences occurred twice. The patient was cured after the administration of amphotericin B for 5 weeks and monthly prophylaxis for 6 months.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Amphotericin B / therapeutic use*
Antiprotozoal Agents / therapeutic use*
Child, Preschool
Female
Humans
Leishmania / classification*
Leishmaniasis / drug therapy*
Leishmaniasis / parasitology*
Leishmaniasis / pathology
Recurrence

Substances

Antiprotozoal Agents
Amphotericin B