The changing face of the henipaviruses

Vet Microbiol. 2013 Nov 29;167(1-2):151-8. doi: 10.1016/j.vetmic.2013.08.002. Epub 2013 Aug 13.

Abstract

The Henipavirus genus represents a group of paramyxoviruses that are some of the deadliest of known human and veterinary pathogens. Hendra and Nipah viruses are zoonotic pathogens that can cause respiratory and encephalitic illness in humans with mortality rates that exceed 70%. Over the past several years, we have seen an increase in the number of cases and an altered clinical presentation of Hendra virus in naturally infected horses. Recent increase in the number of cases has also been reported with human Nipah virus infections in Bangladesh. These factors, along with the recent discovery of henipa and henipa-like viruses in Africa, Asia and South and Central America adds, a truly global perspective to this group of emerging viruses.

Keywords: Hendra virus; Henipa-like viruses; Henipavirus; Nipah virus; Zoonosis.

Publication types

  • Review

MeSH terms

  • Africa
  • Animals
  • Asia
  • Hendra Virus / classification
  • Hendra Virus / physiology
  • Henipavirus / classification*
  • Henipavirus / physiology*
  • Henipavirus Infections / epidemiology
  • Henipavirus Infections / mortality
  • Henipavirus Infections / prevention & control
  • Henipavirus Infections / transmission
  • Henipavirus Infections / virology*
  • Horse Diseases / epidemiology
  • Horse Diseases / mortality
  • Horse Diseases / prevention & control
  • Horse Diseases / transmission
  • Horses
  • Humans
  • Nipah Virus / classification
  • Nipah Virus / physiology
  • Zoonoses / epidemiology
  • Zoonoses / prevention & control
  • Zoonoses / virology