Abstract
The urinary tract is a common source for life-threatening infections. Most patients with sepsis or septic shock from a urinary source have complicated urinary tract infection. This article explains the epidemiology, risk factors, and treatment. Effective management, appropriate collection of microbiology specimens, prompt initiation of antimicrobial therapy, source control, and supportive therapy are described.
Keywords:
Bacteremia; Complicated urinary infection; Pyelonephritis; Urosepsis.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Acute Disease
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Aminoglycosides / therapeutic use*
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Amphotericin B / therapeutic use
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Anti-Infective Agents / therapeutic use*
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Antifungal Agents / therapeutic use*
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Catheters, Indwelling / adverse effects
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Catheters, Indwelling / microbiology
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Community-Acquired Infections
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Cross Infection
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Deoxycholic Acid / therapeutic use
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Drug Combinations
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Female
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Fluconazole / therapeutic use
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Humans
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Male
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Prognosis
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Risk Factors
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Shock, Septic / complications*
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Shock, Septic / microbiology
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Urinary Tract / abnormalities*
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Urinary Tract / microbiology
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Urinary Tract Infections* / complications
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Urinary Tract Infections* / drug therapy
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Urinary Tract Infections* / epidemiology
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Urinary Tract Infections* / microbiology
Substances
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Aminoglycosides
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Anti-Infective Agents
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Antifungal Agents
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Drug Combinations
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Deoxycholic Acid
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Amphotericin B
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amphotericin B, deoxycholate drug combination
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Fluconazole