Hookworm-related cutaneous larva migrans in northern Brazil: resolution of clinical pathology after a single dose of ivermectin

Clin Infect Dis. 2013 Oct;57(8):1155-7. doi: 10.1093/cid/cit440. Epub 2013 Jun 27.

Abstract

To assess the effect of ivermectin on the morbidity caused by hookworm-related cutaneous larva migrans in patients in hyperendemic areas, we treated 92 patients (with 441 tracks in total) from Manaus, Brazil, with single-dose ivermectin (200 µg/kg). Four weeks later, patients had 60 tracks, and the associated morbidity improved significantly.

Keywords: Brazil; HrCLM; clinical pathology; endemic area; ivermectin.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Antiparasitic Agents / administration & dosage*
  • Brazil / epidemiology
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Endemic Diseases
  • Female
  • Hookworm Infections / drug therapy*
  • Hookworm Infections / epidemiology
  • Hookworm Infections / parasitology
  • Humans
  • Ivermectin / administration & dosage*
  • Larva Migrans / drug therapy*
  • Larva Migrans / epidemiology
  • Larva Migrans / parasitology
  • Male
  • Middle Aged
  • Young Adult

Substances

  • Antiparasitic Agents
  • Ivermectin