Matrix-assisted laser desorption ionization-time of flight mass spectrometry is a sensitive and specific method for identification of aerococci

Erik Senneby; Bo Nilson; Ann-Cathrine Petersson; Magnus Rasmussen

doi:10.1128/JCM.02637-12

Matrix-assisted laser desorption ionization-time of flight mass spectrometry is a sensitive and specific method for identification of aerococci

J Clin Microbiol. 2013 Apr;51(4):1303-4. doi: 10.1128/JCM.02637-12. Epub 2013 Feb 6.

Authors

Erik Senneby¹, Bo Nilson, Ann-Cathrine Petersson, Magnus Rasmussen

Affiliation

¹ Clinical Microbiology, University and Regional Laboratories, Region Skåne, Lund, Sweden. erik.senneby@med.lu.se

Abstract

Conventional methods for the identification of human-pathogenic aerococci to the species level are not reliable. We show that matrix-assisted laser desorption ionization-time of flight mass spectrometry correctly identifies aerococci to the species level and that it can be used to identify aerococci with high specificity in the diagnostic clinical microbiology laboratory.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Aerococcus / chemistry*
Aerococcus / classification*
Aerococcus / isolation & purification
Bacteriological Techniques / methods*
Gram-Positive Bacterial Infections / diagnosis
Gram-Positive Bacterial Infections / microbiology
Humans
Sensitivity and Specificity
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods*