Ciprofloxacin-resistant Aeromonas hydrophila cellulitis following leech therapy

J Clin Microbiol. 2013 Apr;51(4):1324-6. doi: 10.1128/JCM.03217-12. Epub 2013 Jan 30.

Abstract

We report a case of surgical site infection with ciprofloxacin-resistant Aeromonas hydrophila following leech therapy. Antimicrobial and genetic analyses of leech and patient isolates demonstrated that the resistant isolates originated from the leech gut microbiota. These data suggest that ciprofloxacin monotherapy as a prophylaxis regimen prior to leech therapy may not be effective in preventing infection.

Publication types

  • Case Reports

MeSH terms

  • Aeromonas hydrophila / drug effects
  • Aeromonas hydrophila / isolation & purification*
  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Cellulitis / diagnosis*
  • Cellulitis / microbiology
  • Cellulitis / pathology
  • Child
  • Ciprofloxacin / pharmacology*
  • Drug Resistance, Bacterial*
  • Female
  • Gastrointestinal Tract / microbiology
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / microbiology
  • Gram-Negative Bacterial Infections / pathology
  • Hirudo medicinalis / microbiology
  • Humans
  • Leeching / adverse effects*
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / microbiology
  • Surgical Wound Infection / pathology

Substances

  • Anti-Bacterial Agents
  • Ciprofloxacin