Capnocytophaga bacteraemia following rituximab treatment

BMJ Case Rep. 2012 Aug 13:2012:bcr2012006224. doi: 10.1136/bcr-2012-006224.

Abstract

A case is presented of Capnocytophaga bacteraemia, in a juvenile chronic arthritis (JCA) patient receiving steroids, methotrexate and rituximab. This Gram-negative bacillus commonly found in dog saliva has been described to cause illness in immune compromised hosts such as oncology patients, those receiving cytotoxic or biological drugs, alcoholics or postsplenectomy. To the best of our knowledge, this is the first report of Capnocytophaga bacteraemia following rituximab treatment.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Monoclonal, Murine-Derived / adverse effects*
  • Antirheumatic Agents / adverse effects*
  • Arthritis, Juvenile / drug therapy
  • Arthritis, Juvenile / immunology
  • Bacteremia / drug therapy
  • Bacteremia / immunology
  • Bacteremia / microbiology*
  • Capnocytophaga*
  • Female
  • Gram-Negative Bacterial Infections / drug therapy
  • Gram-Negative Bacterial Infections / immunology
  • Gram-Negative Bacterial Infections / microbiology*
  • Humans
  • Immunocompromised Host
  • Rituximab
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Antibodies, Monoclonal, Murine-Derived
  • Antirheumatic Agents
  • Rituximab