Outbreak of carbapenem-resistant Providencia stuartii in an intensive care unit

Infect Control Hosp Epidemiol. 2012 Jun;33(6):627-30. doi: 10.1086/665730. Epub 2012 Apr 24.

Abstract

Outbreaks by carbapenem-resistant Providencia stuartii (CRPS) are rarely described. Clinical characteristics of patients with CRPS in an intensive care unit and resistance mechanisms were investigated. Carbapenemase production and/or outer membrane alterations were not detected; only CTX-M-2 and AmpC hyperproduction were noted. The outbreak was ultimately controlled in a 3-month period.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / metabolism
  • Biomarkers / metabolism
  • Brazil
  • Carbapenems / pharmacology
  • Cross Infection / diagnosis
  • Cross Infection / epidemiology*
  • Cross Infection / microbiology
  • Cross Infection / prevention & control
  • Disease Outbreaks* / prevention & control
  • Enterobacteriaceae Infections / diagnosis
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology
  • Enterobacteriaceae Infections / prevention & control
  • Female
  • Humans
  • Infection Control
  • Intensive Care Units*
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Providencia* / drug effects
  • Providencia* / isolation & purification
  • Providencia* / metabolism
  • beta-Lactam Resistance*
  • beta-Lactamases / metabolism

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Biomarkers
  • Carbapenems
  • beta-lactamase CTX-2
  • AmpC beta-lactamases
  • beta-Lactamases