Abstract
The continuous threat of influenza pandemics determines the urgency and necessity to develop safe and effective vaccines against divergent influenza viruses. This review describes the advancements in the research and development of universal influenza vaccines based on the relatively conserved sequences of M2e, HA, and other proteins of influenza viruses.
Copyright 2010 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Biomedical Research / trends*
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Conserved Sequence
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Hemagglutinins, Viral / genetics
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Hemagglutinins, Viral / immunology
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Humans
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Influenza Vaccines / genetics*
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Influenza Vaccines / immunology*
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Influenza, Human / epidemiology*
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Influenza, Human / prevention & control*
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Vaccines, Subunit / genetics
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Vaccines, Subunit / immunology
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Viral Matrix Proteins / genetics
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Viral Matrix Proteins / immunology
Substances
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Hemagglutinins, Viral
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Influenza Vaccines
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M2 protein, Influenza A virus
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Vaccines, Subunit
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Viral Matrix Proteins
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hemagglutinin fusogenic peptide, influenza virus