Antigenic relationships among the rickettsiae of the spotted fever and typhus groups

FEMS Microbiol Lett. 1991 Jul 1;65(3):341-4. doi: 10.1016/0378-1097(91)90238-6.

Abstract

Using immunoblots to analyze antigenic relationships among the pathogenic spotted fever and typhus group rickettsiae, I found that the rickettsial lipopolysaccharide (LPS) was a group-specific antigen. All the rickettsiae examined had 135-kDa and 58-kDa protein antigens. The spotted fever rickettsiae and Rickettsia canada had, in addition, 190-kDa protein antigens which were antigenic analogs of previously described protective antigens of R. conorii and R. rickettsii.

MeSH terms

  • Animals
  • Antigens, Bacterial / immunology*
  • Bacterial Proteins / immunology
  • Blotting, Western
  • Cell Fractionation
  • Electrophoresis, Polyacrylamide Gel
  • Guinea Pigs
  • Immune Sera
  • Lipopolysaccharides / immunology
  • Rickettsia / classification*
  • Rickettsia / immunology
  • Rickettsia Infections / microbiology
  • Rickettsia prowazekii / classification
  • Rickettsia prowazekii / immunology
  • Rickettsia rickettsii / classification
  • Rickettsia rickettsii / immunology
  • Rickettsia typhi / classification
  • Rickettsia typhi / immunology

Substances

  • Antigens, Bacterial
  • Bacterial Proteins
  • Immune Sera
  • Lipopolysaccharides