Abstract
Using immunoblots to analyze antigenic relationships among the pathogenic spotted fever and typhus group rickettsiae, I found that the rickettsial lipopolysaccharide (LPS) was a group-specific antigen. All the rickettsiae examined had 135-kDa and 58-kDa protein antigens. The spotted fever rickettsiae and Rickettsia canada had, in addition, 190-kDa protein antigens which were antigenic analogs of previously described protective antigens of R. conorii and R. rickettsii.
MeSH terms
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Animals
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Antigens, Bacterial / immunology*
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Bacterial Proteins / immunology
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Blotting, Western
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Cell Fractionation
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Electrophoresis, Polyacrylamide Gel
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Guinea Pigs
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Immune Sera
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Lipopolysaccharides / immunology
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Rickettsia / classification*
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Rickettsia / immunology
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Rickettsia Infections / microbiology
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Rickettsia prowazekii / classification
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Rickettsia prowazekii / immunology
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Rickettsia rickettsii / classification
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Rickettsia rickettsii / immunology
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Rickettsia typhi / classification
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Rickettsia typhi / immunology
Substances
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Antigens, Bacterial
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Bacterial Proteins
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Immune Sera
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Lipopolysaccharides