Pharyngeal colonization by Kingella kingae in children with invasive disease

Pediatr Infect Dis J. 2009 Feb;28(2):155-7. doi: 10.1097/INF.0b013e318184dbb8.

Abstract

Kingella kingae organisms isolated from the blood of 3 children with invasive infections were identical by pulsed field gel electrophoresis and random amplified polymorphic DNA-polymerase chain reaction analysis to those recovered from the patients' pharynx, demonstrating the likely role of upper respiratory tract colonization in the pathogenesis of the disease caused by this bacterium.

Publication types

  • Case Reports

MeSH terms

  • Amoxicillin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Cephalexin / therapeutic use
  • Electrophoresis, Gel, Pulsed-Field
  • Female
  • Humans
  • Infant
  • Kingella kingae / genetics
  • Kingella kingae / isolation & purification*
  • Male
  • Neisseriaceae Infections / drug therapy
  • Neisseriaceae Infections / microbiology*
  • Pharynx / microbiology*
  • Random Amplified Polymorphic DNA Technique

Substances

  • Anti-Bacterial Agents
  • Amoxicillin
  • Cephalexin