Case report: human herpesvirus 6 reactivation associated with colitis in a lung transplant recipient

F Lamoth; P Y Jayet; J D Aubert; S Rotman; C Mottet; R Sahli; I Lautenschlager; M Pascual; P Meylan

doi:10.1002/jmv.21268

Case report: human herpesvirus 6 reactivation associated with colitis in a lung transplant recipient

J Med Virol. 2008 Oct;80(10):1804-7. doi: 10.1002/jmv.21268.

Authors

F Lamoth¹, P Y Jayet, J D Aubert, S Rotman, C Mottet, R Sahli, I Lautenschlager, M Pascual, P Meylan

Affiliation

¹ Department of Internal Medicine, Infectious Diseases Service, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Frederic.Lamoth@chuv.ch

PMID: 18712834
DOI: 10.1002/jmv.21268

Abstract

Whereas human herpesvirus 6 (HHV-6) reactivation is frequent in solid organ transplant recipients, symptomatic disease is rare. A case of colitis associated with HHV-6B reactivation was observed in a lung transplant recipient. This case report suggests that symptomatic HHV-6 infection may occur in the absence of detectable viremia.

MeSH terms

Adult
Biopsy
Colitis / diagnosis*
Colitis / pathology
Colitis / virology*
Colon / pathology
Colon / virology
DNA, Viral / genetics
DNA, Viral / isolation & purification
Herpesvirus 6, Human / isolation & purification
Herpesvirus 6, Human / physiology*
Humans
Intestinal Mucosa / pathology
Intestinal Mucosa / virology
Lung Transplantation / adverse effects*
Male
Polymerase Chain Reaction
Pulmonary Disease, Chronic Obstructive / surgery*
Roseolovirus Infections / complications
Roseolovirus Infections / diagnosis*
Virus Activation

Substances

DNA, Viral