Surveillance of community-based reservoirs reveals the presence of CTX-M, imported AmpC, and OXA-30 beta-lactamases in urine isolates of Klebsiella pneumoniae and Escherichia coli in a U.S. community

Antimicrob Agents Chemother. 2008 Oct;52(10):3814-6. doi: 10.1128/AAC.00877-08. Epub 2008 Jul 28.

Abstract

beta-Lactamases produced by urine isolates from patients in long-term care facilities (LTCFs), outpatient, clinics, and one hospital in a U.S. community were characterized. A total of 1.3% of all Escherichia coli and Klebsiella pneumoniae isolates collected from patients in 30 LTCFs and various outpatient clinics produced extended-spectrum beta-lactamases (ESBLs) and/or imported AmpC beta-lactamases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / biosynthesis
  • Bacterial Proteins / genetics
  • Community-Acquired Infections / epidemiology
  • Community-Acquired Infections / microbiology*
  • Disease Reservoirs / microbiology
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Escherichia coli / isolation & purification
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / microbiology*
  • Humans
  • Klebsiella Infections / epidemiology
  • Klebsiella Infections / microbiology*
  • Klebsiella pneumoniae* / enzymology
  • Klebsiella pneumoniae* / genetics
  • Klebsiella pneumoniae* / isolation & purification
  • Population Surveillance
  • United States / epidemiology
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • Bacterial Proteins
  • beta-lactamase OXA-30
  • AmpC beta-lactamases
  • beta-Lactamases