Activity of meropenem against antibiotic-resistant or infrequently encountered gram-negative bacilli

Antimicrob Agents Chemother. 1991 Nov;35(11):2410-4. doi: 10.1128/AAC.35.11.2410.

Abstract

Meropenem was compared in vitro with imipenem as well as with several other contemporary beta-lactams, ciprofloxacin, and gentamicin against a group of highly antibiotic resistant members of the family Enterobacteriaceae and a collection of oxidase-positive and/or glucose-nonfermentative gram-negative bacilli. In this study, meropenem was more active than imipenem against isolates of Enterobacter, Klebsiella, Morganella, Providencia, Alcaligenes, Aeromonas, and Pasteurella.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Resistance, Microbial
  • Gram-Negative Bacteria / drug effects*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Meropenem
  • Microbial Sensitivity Tests
  • Thienamycins / pharmacology*

Substances

  • Thienamycins
  • Meropenem