Abstract
We describe the first IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19, which differed from IMP-2 by a single amino acid change (Arg to Ala at position 38). bla(IMP-19) was found within a class 1 integron located on a 35-kb plasmid. This is also the first description of an IMP producer in France.
MeSH terms
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Aeromonas / drug effects
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Aeromonas / enzymology
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Aeromonas / genetics*
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Anti-Bacterial Agents / pharmacology
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France
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Integrons / genetics*
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Kinetics
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Microbial Sensitivity Tests
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Molecular Sequence Data
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Plasmids / genetics*
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Sequence Analysis, DNA
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Substrate Specificity
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beta-Lactamases / genetics*
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beta-Lactamases / metabolism
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beta-Lactams / pharmacology
Substances
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Anti-Bacterial Agents
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beta-Lactams
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beta-lactamase IMP-1
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beta-Lactamases