Introduction of Haemophilus influenzae type B conjugate vaccine into routine immunization in Ghana and its impact on bacterial meningitis in children younger than five years

Pediatr Infect Dis J. 2007 Apr;26(4):356-8. doi: 10.1097/01.inf.0000258693.19247.8e.

Abstract

This report shows the impact of a pentavalent vaccine that includes Haemophilus influenzae type b (Hib) conjugate vaccine on bacterial meningitis in children younger than 5 years in Ghana. A review of the first 3 years of a pediatric bacterial meningitis surveillance program, started in August 2001 in Accra, Ghana, was undertaken. There was a significant reduction, P = 0.042 and 0.017, in percentage of purulent meningitis in children younger than 1 year, comparing the first year when the vaccine was introduced, to the second and third years, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Ghana / epidemiology
  • Haemophilus Vaccines / administration & dosage*
  • Haemophilus Vaccines / immunology
  • Haemophilus influenzae type b / immunology*
  • Haemophilus influenzae type b / isolation & purification
  • Humans
  • Immunization Programs*
  • Incidence
  • Infant
  • Meningitis, Bacterial / epidemiology*
  • Meningitis, Bacterial / microbiology
  • Meningitis, Bacterial / prevention & control*
  • Meningitis, Haemophilus / epidemiology
  • Meningitis, Haemophilus / microbiology
  • Meningitis, Haemophilus / prevention & control
  • Neisseria meningitidis / isolation & purification
  • Streptococcus pneumoniae / isolation & purification
  • Vaccines, Conjugate / administration & dosage*
  • Vaccines, Conjugate / immunology

Substances

  • Haemophilus Vaccines
  • Vaccines, Conjugate