Abstract
Given the recent report of a false-positive result in the Platelia Aspergillus enzyme immunoassay in a patient with cryptococcosis and in yeast extracts and purified galactoxylomannan of Cryptococcus neoformans, we evaluated culture extracts, purified polysaccharides, clinical specimens, and specimens from animals following experimental infection. Our results revealed no cross-reactions.
Publication types
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Clinical Trial
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Research Support, N.I.H., Extramural
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Research Support, N.I.H., Intramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Aspergillus fumigatus / immunology*
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Carbohydrate Sequence
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Cross Reactions*
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Cryptococcus neoformans / immunology*
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Immunoenzyme Techniques
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Mice
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Mice, Inbred BALB C
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Polysaccharides
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Polysaccharides, Bacterial / chemistry*
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Polysaccharides, Bacterial / immunology*
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Rabbits
Substances
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Polysaccharides
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Polysaccharides, Bacterial
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galactoxylomannan