Abstract
We observed false-positive results in the Platelia Aspergillus enzyme-linked immunoassay (EIA) for specimens from patients with histoplasmosis and mice with experimental infection. Platelia Aspergillus EIA-positive specimens were negative in the second-generation Histoplasma antigen EIA. Care must be taken to exclude histoplasmosis for patients with positive Platelia Aspergillus EIA results.
Publication types
-
Clinical Trial
-
Research Support, N.I.H., Intramural
MeSH terms
-
Animals
-
Antibodies, Fungal*
-
Antigens, Fungal / blood*
-
Aspergillosis, Allergic Bronchopulmonary / diagnosis
-
Cross Reactions
-
Disease Models, Animal
-
Enzyme-Linked Immunosorbent Assay / methods*
-
Galactose / analogs & derivatives
-
Histoplasmosis / blood*
-
Histoplasmosis / immunology*
-
Humans
-
Mannans / immunology
-
Mice
-
Rabbits
Substances
-
Antibodies, Fungal
-
Antigens, Fungal
-
Mannans
-
galactomannan
-
Galactose