Early diagnosis of Acanthamoeba infection during routine cytological examination of cerebrospinal fluid

J Clin Microbiol. 2006 May;44(5):1903-4. doi: 10.1128/JCM.44.5.1903-1904.2006.

Abstract

Early identification of Acanthamoeba in cerebrospinal fluid is mandatory to prevent fatal granulomatous amebic encephalitis. In the case presented here amebic trophozoites were detected in a routine cerebrospinal fluid sample. The antibiotic treatment and the apparently low virulence of this isolate were responsible for the benign progression of the infection.

Publication types

  • Case Reports

MeSH terms

  • Acanthamoeba / genetics
  • Acanthamoeba / isolation & purification*
  • Acanthamoeba / pathogenicity
  • Amebiasis / cerebrospinal fluid
  • Amebiasis / diagnosis*
  • Amebiasis / drug therapy
  • Amebiasis / parasitology
  • Amebicides / therapeutic use
  • Animals
  • Cerebrospinal Fluid / parasitology
  • DNA, Protozoan / genetics
  • DNA, Protozoan / isolation & purification
  • Encephalitis / cerebrospinal fluid
  • Encephalitis / diagnosis*
  • Encephalitis / drug therapy
  • Encephalitis / parasitology
  • Female
  • Humans
  • Middle Aged
  • Molecular Sequence Data
  • RNA, Protozoan / genetics
  • RNA, Ribosomal, 18S / genetics

Substances

  • Amebicides
  • DNA, Protozoan
  • RNA, Protozoan
  • RNA, Ribosomal, 18S

Associated data

  • GENBANK/DQ103890