Clostridium difficile-associated disease: new challenges from an established pathogen

Cleve Clin J Med. 2006 Feb;73(2):187-97. doi: 10.3949/ccjm.73.2.187.

Abstract

Clostridium difficile-associated disease (CDAD) can range from uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing, possibly due to a new strain. Transmission of C difficile occurs primarily in health care facilities via the fecal-oral route following transient contamination of the hands of health care workers and patients; contamination of the patient care environment also plays an important role.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Anti-Infective Agents / adverse effects
  • Anti-Infective Agents / therapeutic use
  • Clostridioides difficile / isolation & purification
  • Clostridioides difficile / pathogenicity*
  • Clostridium Infections / diagnosis*
  • Clostridium Infections / drug therapy*
  • Clostridium Infections / prevention & control
  • Cross Infection / diagnosis*
  • Cross Infection / drug therapy*
  • Cross Infection / prevention & control
  • Diagnosis, Differential
  • Disease Progression
  • Humans
  • Infection Control / methods
  • Risk Factors

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents