Comparison of the Binax NOW Flu A enzyme immunochromatographic assay and R-Mix shell vial culture for the 2003-2004 influenza season

J Clin Microbiol. 2005 Dec;43(12):6133-5. doi: 10.1128/JCM.43.12.6133-6135.2005.

Abstract

The Binax NOW Flu A enzyme immunochromatographic assay was compared to viral culture with R-Mix shell vials for 455 nasal-wash or nasal-aspirate specimens. The overall sensitivity, specificity, positive predictive value, and negative predictive value of the assay were 64.9%, 98.4%, 89.3%, and 93.2%, respectively. However, the assay sensitivity decreased significantly with increasing patient age.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Chromatography / methods
  • Humans
  • Immunoenzyme Techniques / methods*
  • Infant
  • Infant, Newborn
  • Influenza A Virus, H3N2 Subtype / isolation & purification*
  • Influenza B virus / isolation & purification*
  • Influenza, Human / diagnosis*
  • Influenza, Human / virology*
  • Middle Aged
  • Predictive Value of Tests
  • Reagent Kits, Diagnostic*
  • Seasons
  • Sensitivity and Specificity
  • Virus Cultivation

Substances

  • Reagent Kits, Diagnostic