Multifocal sporotrichosis with meningeal involvement in a patient with AIDS

Med Mycol. 2005 Mar;43(2):187-90. doi: 10.1080/13693780500035904.

Abstract

This report describes a 29-year-old man with AIDS and disseminated lymphocutaneous sporotrichosis diagnosis presenting a poor therapeutic adhesion to itraconazole therapy that later evolved to neurological impairment and death. Necropsy showed granulomatous reaction and yeast-like forms similar to Sporothrix schenckii in meninges, lymph nodes, marrow bone, skin, testicles, epididymides and pancreas. Meningeal sporotrichosis cases associated to AIDS are reviewed in brief.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications*
  • Adult
  • Antifungal Agents / therapeutic use
  • Brazil
  • Humans
  • Itraconazole / therapeutic use
  • Male
  • Meningitis, Fungal / complications*
  • Meningitis, Fungal / microbiology
  • Meningitis, Fungal / pathology
  • Sporothrix / drug effects
  • Sporothrix / isolation & purification
  • Sporotrichosis / complications*
  • Sporotrichosis / drug therapy
  • Sporotrichosis / pathology

Substances

  • Antifungal Agents
  • Itraconazole