Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation

G Bogdanovic; P Priftakis; G Giraud; M Kuzniar; R Ferraldeschi; P Kokhaei; H Mellstedt; M Remberger; P Ljungman; J Winiarski; T Dalianis

doi:10.1128/JCM.42.11.5394-5396.2004

Association between a high BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation

J Clin Microbiol. 2004 Nov;42(11):5394-6. doi: 10.1128/JCM.42.11.5394-5396.2004.

Authors

G Bogdanovic¹, P Priftakis, G Giraud, M Kuzniar, R Ferraldeschi, P Kokhaei, H Mellstedt, M Remberger, P Ljungman, J Winiarski, T Dalianis

Affiliation

¹ Department of Oncology-Pathology, Karolinska Institute, Hudding University Hospital, Stockholm, Sweden.

Abstract

BK virus (BKV) load in urine alone or in combination with acute graft-versus-host disease (GVHD) was correlated to development of hemorrhagic cystitis (HC). BKV load in combination with acute GVHD discriminated the best, while BKV and viral load alone, but not GVHD, still showed predictive ability for HC.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
BK Virus / physiology*
Child
Cystitis / etiology*
Graft vs Host Disease / complications*
Graft vs Host Disease / virology
Hematopoietic Stem Cell Transplantation / adverse effects*
Hemorrhage / etiology*
Humans
Polyomavirus Infections / complications
Polyomavirus Infections / virology
Tumor Virus Infections / complications
Tumor Virus Infections / virology
Urine / virology*
Viral Load