Abstract
Eight clones of monoclonal antibodies (Mabs) to Nipah virus (NV) were produced against formalin-inactivated NV antigens. They reacted positive by indirect immunofluorescent antibody test, and one of them also demonstrated virus neutralizing activity. They were classified into six different types based on their biological properties. These Mabs will be useful for immunodiagnosis of NV infections in animals and further research studies involving the genomes and proteins of NV.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Monoclonal / isolation & purification*
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Chlorocebus aethiops
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Disease Outbreaks / veterinary
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Formaldehyde
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Henipavirus Infections / epidemiology
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Henipavirus Infections / veterinary*
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Malaysia / epidemiology
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Mice
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Mice, Inbred BALB C
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Neutralization Tests
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Nipah Virus / immunology*
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Nipah Virus / isolation & purification
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Swine
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Swine Diseases / epidemiology
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Swine Diseases / virology*
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Vero Cells
Substances
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Antibodies, Monoclonal
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Formaldehyde