Abstract
Vancomycin-resistant Enterococcus faecalis coisolated with vancomycin-resistant (VanA) Staphylococcus aureus was found to contain two plasmids, designated pAM830 (45 kb) and pAM831 (95 kb). pAM830, found to be conjugative and closely related to the Inc18 family of broad-host-range conjugative plasmids, encodes resistances to vancomycin (via a Tn1546-like element) and erythromycin; pAM831 encodes resistances to gentamicin, streptomycin, and erythromycin.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Bacterial Proteins / genetics*
-
Carbon-Oxygen Ligases / genetics*
-
Conjugation, Genetic
-
DNA Transposable Elements / genetics
-
DNA, Bacterial / genetics
-
Electrophoresis, Gel, Pulsed-Field
-
Enterococcus faecalis / drug effects*
-
Enterococcus faecalis / genetics*
-
Humans
-
Methicillin Resistance / genetics
-
Plasmids / genetics*
-
Staphylococcal Infections / microbiology*
-
Staphylococcus aureus / genetics*
-
Vancomycin Resistance / genetics*
Substances
-
Bacterial Proteins
-
DNA Transposable Elements
-
DNA, Bacterial
-
VanA ligase, Bacteria
-
Carbon-Oxygen Ligases