Multidrug-resistant tuberculosis in a lung transplant recipient

J Heart Lung Transplant. 2003 Oct;22(10):1168-73. doi: 10.1016/s1053-2498(02)01189-0.

Abstract

Tuberculosis infection has been a relatively rare complication after lung transplantation. However, as more countries in which Mycobacterium tuberculosis infection remains endemic embark on lung transplant programs, the occurrence of multidrug-resistant tuberculosis after transplantation is a genuine threat. We report the first case of multidrug-resistant tuberculosis in a double-lung transplant recipient who probably acquired the disease from the donor. We discuss the problems in clinical management of post-transplant tuberculosis infection and of drug-resistance.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lung Transplantation*
  • Radiography
  • Tissue Donors
  • Tuberculosis, Multidrug-Resistant / diagnostic imaging
  • Tuberculosis, Multidrug-Resistant / drug therapy
  • Tuberculosis, Multidrug-Resistant / epidemiology*
  • Tuberculosis, Multidrug-Resistant / transmission
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / drug therapy
  • Tuberculosis, Pulmonary / epidemiology*
  • Tuberculosis, Pulmonary / transmission

Substances

  • Antitubercular Agents
  • Immunosuppressive Agents