Abstract
We evaluated 117 isolates of Mycobacterium tuberculosis for susceptibility to linezolid by the proportion and E-test methods. Linezolid showed high in vitro activity, with all the strains inhibited by <or=1 microg of the drug per ml. E-test MICs were at least 4 dilutions lower than their equivalents by the standard proportion method.
MeSH terms
-
Acetamides / pharmacology*
-
Antitubercular Agents / pharmacology*
-
Humans
-
Linezolid
-
Microbial Sensitivity Tests
-
Mycobacterium tuberculosis / drug effects*
-
Mycobacterium tuberculosis / isolation & purification
-
Oxazolidinones / pharmacology*
-
Tuberculosis, Multidrug-Resistant*
Substances
-
Acetamides
-
Antitubercular Agents
-
Oxazolidinones
-
Linezolid