Endocarditis caused by methicillin-resistant Staphylococcus aureus: treatment failure with linezolid

Maria E Ruiz; Isabel C Guerrero; Carmelita U Tuazon

doi:10.1086/342698

Endocarditis caused by methicillin-resistant Staphylococcus aureus: treatment failure with linezolid

Clin Infect Dis. 2002 Oct 15;35(8):1018-20. doi: 10.1086/342698. Epub 2002 Sep 26.

Authors

Maria E Ruiz¹, Isabel C Guerrero, Carmelita U Tuazon

Affiliation

¹ Department of Medicine, George Washington University Medical Center, Washington, DC 20037, USA.

PMID: 12355391
DOI: 10.1086/342698

Abstract

We describe 2 cases of endocarditis caused by methicillin-resistant Staphylococcus aureus that failed to respond to intravenous linezolid therapy but were successfully treated with trimethoprim-sulfamethoxazole plus gentamicin and vancomycin plus rifampin.

Publication types

Case Reports

MeSH terms

Acetamides / therapeutic use*
Aged
Anti-Bacterial Agents / therapeutic use*
Endocarditis, Bacterial / drug therapy*
Humans
Linezolid
Methicillin Resistance / physiology*
Oxazolidinones / therapeutic use*
Staphylococcal Infections / drug therapy*
Staphylococcus aureus* / drug effects
Treatment Failure

Substances

Acetamides
Anti-Bacterial Agents
Oxazolidinones
Linezolid