Penicillin treatment of neurosyphilis. Are recommended dosages sufficient?

JAMA. 1975 Apr 21;232(3):270-1.

Abstract

A 60-year-old man with symptomatic neurosyphilis was treated with penicillin G procaine in the dosages recommended by the Public Health Service, and a less than spirocheticidal level of penicillin G was found in the cerebrospinal fluid.

MeSH terms

  • Humans
  • Injections, Intramuscular
  • Injections, Intravenous
  • Male
  • Methods
  • Middle Aged
  • Neurosyphilis / drug therapy*
  • Penicillin G Benzathine / therapeutic use
  • Penicillin G Procaine / blood
  • Penicillin G Procaine / cerebrospinal fluid
  • Penicillin G Procaine / therapeutic use*
  • Penicillins / therapeutic use
  • Time Factors

Substances

  • Penicillins
  • Penicillin G Procaine
  • Penicillin G Benzathine