Bacteriostatic and bactericidal activities of moxifloxacin against Coxiella burnetii

J M Rolain; M Maurin; D Raoult

doi:10.1128/AAC.45.1.301-302.2001

Bacteriostatic and bactericidal activities of moxifloxacin against Coxiella burnetii

Antimicrob Agents Chemother. 2001 Jan;45(1):301-2. doi: 10.1128/AAC.45.1.301-302.2001.

Authors

J M Rolain¹, M Maurin, D Raoult

Affiliation

¹ Unité des Rickettsies CNRS UPRES-A 6020, Faculté de Médecine, Université de la Méditerranée, 13385 Marseille Cedex 05, France.

Abstract

The in vitro activity of moxifloxacin against Coxiella burnetii was compared to those of pefloxacin, ofloxacin, and doxycycline. MICs of moxifloxacin ranged from 0.5 to 1 microg/ml for the Nine Mile, Priscilla, and Q212 strains. Moxifloxacin was not bactericidal against C. burnetii at 4 microg/ml.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Infective Agents / pharmacology*
Aza Compounds*
Coxiella burnetii / drug effects*
Fluoroquinolones*
Humans
Microbial Sensitivity Tests
Moxifloxacin
Q Fever / microbiology
Quinolines*

Substances

Anti-Infective Agents
Aza Compounds
Fluoroquinolones
Quinolines
Moxifloxacin